This collection primarily contains the correspondence of James W. Anderson (1797-1881), his wife Mary Minor Anderson (1810-1865), and their son Captain James Anderson (1831-1920).

This collection contains correspondence and ephemera related to Adolphus Cooke, a Confederate soldier, and his family, circa 1862-1915.

This collection contains the correspondence of Dr. John Hanson Thomas sent during his imprisonment during the Civil War. Dr. Thomas and his wife, Annie Campbell Thomas, née Gordon, wrote each other almost every day during his time as a prisoner of war from September 1861 to February 1862, and letters between the couple make up the majority of the collection. These letters discuss daily life in the prison camp, political views, current events, and family matters.